The tribe was bordered on the north-east by the Venicones, on the north-west possibly by the Caledoni, to the west by the Epidii, on the east by the Selgovae and to the south by the Novantae. Other passages in Ptolemy give the ancient names of other geographical features within the territories of the Damnoni tribe:
The Damnoni territories encompassed much of southern Strathclyde, comprising the old (i.e. pre-1974) counties of Renfrewshire, Lanarkshire and Ayrshire. Nowadays these lands are used for dairying and hill farming, with root crops being grown in a narrow coastal strip to the north and south-west of Ayr, also in the area of Glasgow to the north-east and along Clydesdale to the south-west; there is no reason to believe that the Damnoni did otherwise.
Geologically, the tribal lands are mainly carboniferous limestone with underlying coal deposits, effectively split in two by extrusive volcanic rocks, which run from Wemyss Bay on the Firth of Clyde south-eastwards to the central Southern Uplands, almost cutting-off Glasgow from the western coastal region. The tribal population, like today, was probably centered in these two areas; that to the north included the modern City of Glasgow and it's outlying suburbs, stretching south-east along Clydesdale from Motherwell to Lanark, while the other settlement area lay along the coastal plain to the west, encompassing the modern towns of Ardrossan, Irvine, Kilmarnock, Ayr and Holmhead.
The name of the principal tribal centre is unknown but is very likely to be listed among the six civil centres ascribed to the tribe by the geographer Ptolemy, who wrote in the mid-second century.
None of the following Romano-British towns, which are attested in the mid-2nd century, have been positively identified, but Ptolemy's coordinates and the place-names themselves lend further clues as to their whereabouts. It should be noted, however, that the latter three towns are all located by Ptolemy to the north of the River Clyde and may have been within the territories of the neighbouring tribe the Venicones.
|Colanica [unknown]||This name is unique in Roman-Britain and does not occur in any other geographical source. It is placed by Ptolemy some distance inland and may possibly represent the military complex and associated civil settlement at Castledykes, close to the border with the Selgovae.|
|Vindogara [Irvine, South Strathclyde]||Probably connected with the bay of the same name (see above), this settlement must have been situated close to the coast, more than likely at Irvine.|
|Coria [unknown]||Ptolemy records another town of this name at Corbridge in Cumbria, and it's name may be connected with the Welsh/Gaelic word for a valley or glen.|
|Alauna [unknown]||The name Alauna occurs a few times in Roman Britain, usually denoting a riverside settlement.|
|Lindum [unknown]||There are a couple of Romano-British towns of this name, which means '(place of) the Black Lake'.|
|Victoria [unknown]||Possibly the site of a major battle sometime during the late-first or early-second centuries.|